What are the steps involved in an IVF cycle?

A complete guide to the IVF treatment timeline.

In vitro fertilization (IVF) is a complex treatment that takes place over several weeks or months for each cycle. Here's a detailed breakdown of the IVF cycle steps:

Initial Consultation and Testing

Before starting IVF, patients undergo comprehensive fertility testing, including:

  • Blood tests to check hormone levels

  • Ultrasound to evaluate ovarian reserve

  • Semen analysis for male partners

  • Uterine examination to ensure healthy implantation environment

Step 1: Ovarian Stimulation

The cycle begins with hormone medications to stimulate the ovaries and produce multiple eggs over 10 to 12 days. This phase involves:

  • Daily hormone injections

  • Regular blood tests to monitor hormone levels

  • Ultrasound monitoring of follicle development

  • Medication adjustments based on response

Step 2: Trigger Shot and Egg Retrieval

Once follicles reach optimal size, a trigger shot is administered to mature eggs. The egg retrieval procedure occurs 36 hours later. This is a minimally invasive procedure under light sedation. The doctor collects mature eggs using ultrasound guidance.

Step 3: Sperm Collection and Fertilization

On egg retrieval day:

  • Fresh sperm sample collection or thawed donor sperm preparation

  • Egg and sperm combination in the lab

  • Possible use of ICSI (intracytoplasmic sperm injection) if needed

Step 4: Embryo Development

During this critical phase:

  • Daily monitoring of embryo development

  • Assessment of embryo quality

  • Possible genetic testing if recommended

  • Selection of best embryos for transfer

Step 5: Embryo Transfer

At this point, eggs may be frozen. If the doctor decides to transfer the selected embryo(s) to the uterus, here’s what happens:

  • It’s a quick, painless procedure requiring no anesthesia

  • Optional cryopreservation of remaining viable embryos

Post-Transfer Care and Monitoring

Following transfer:

  • Progesterone supplementation to support implantation

  • Two-week wait before pregnancy test

  • Blood tests to monitor hormone levels

  • Early pregnancy ultrasound if successful

Timing and Duration

A complete IVF cycle typically takes 4-6 weeks from start to finish. Many patients need multiple cycles to achieve pregnancy.

Important Considerations

  • Following medication schedules precisely

  • Attending all monitoring appointments

  • Managing stress through self-care

  • Understanding potential side effects

  • Having realistic expectations about success rates

Modern IVF protocols continue to evolve with technological advances, improving success rates while minimizing patient discomfort. Consulting with a fertility specialist helps determine the most appropriate protocol based on individual circumstances.